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Scott R. MacKenzie Foundation

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Description

The mission of the Scott R. MacKenzie Foundation is to perpetuate genomic sequencing and research that can impact humanity, improve quality of life, and transform the future health of communities.

The Foundation funds leading-edge human genetic research (DNA, RNA, protein) to advance cures for cancer, lung disease (including asthma), diabetes, and heart disease.  

Nonprofit organizations based in the United States are eligible to apply.

Description
Opportunity Information
Application Deadlines
Application Deadlines
Geographic Scope
Geographic Scope
Areas of Interest
Areas of Interest
Types of Support
Types of Support
Funder Information
Total Annual Giving
$960,916
Type
Type
EIN
EIN
Application Procedures
Application Procedures
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Eligibility Details
Eligibility Details
Contact Information
General Contact
General Contact
Primary Contact
Primary Contact
Grants History

You can review tax forms on ProPublica. Learn more about them and the 990.

990s

This is a list of grant recipients noted on the funder’s 990 forms.

This includes forms filed in 2018 and later, so it can include information for tax years earlier than that.

The information below is pulled directly from the form itself without any alterations.

If the details are not included, e.g. “Various”, they may be indicated on the PDF on the IRS site.

Tax Year Recipient City State / Province Country Amount Purpose
UNIVERSITY OF MIAMI COLLEGE OF MEDICINE Coral Gables FL US $86,571 Year 2 funding - this project seeks to utilize generative adversarial network (gan) models to create high-quality synthetic images representing various prostate cancer (pca) grades. These images will be tailored to account for the morphological and genomic granularity associated with each gleason grade while requiring significantly smaller training data samples. Preliminary data indicates that this approach considerably enhances ai models' prognostic capabilities for pca.
HMH HOSPITALS CORPORATION Edison NJ US $150,000 Year 2 funding - this project seeks to focus on quantifying selective pressures applied by nucleotide depletion and genomic stress in order to dissect the evolutionary dynamics of cancer cells across multiple tumor types, including leukemia, lymphoma, myeloma, colorectal cancer, melanoma, and retinoblastoma.
MOUNT DESERT ISLAND BIOLOGICAL LABORATORY Bar Harbor ME US $450,000 This project seeks to continue the project awarded in 2022 to establish a novel treatment strategy for diabetic kidney disease. Previous support from the mackenzie foundation is allowing mdi bio lab to understand the structure and functional parts of the hpa2 molecule and establish a baseline from which to fully understand its function. Based on this ongoing work, mdi bio lab now seeks to investigate the effect of diabetes in a model organism of aging (african turquoise killifish). Simultaneously, mdi bio lab also proposes to use this model to study the loss of peritubular capillaries observed during kidney aging.
UNIVERSITY OF FLORIDA FOUNDATION Gainesville FL US $149,345 Year 2 funding - this project seeks to identify dependencies of tumor cells in deep margins by performing single-cell sequencing on larger cohort of tumors the grantee collected (n=28) and testing their findings in model systems. Thus, the study would open new avenues for therapies targeting specific traits within tumor cells driving recurrence, and for improved strategies releasing the host immune system against glioblastoma.
UNIVERSITY OF FLORIDA FOUNDATION Gainesville FL US $125,000 Year 2 funding - this project seeks to define treatment regimens of blood thinning medications associated with reduced risk of recurrent heart attacks, which may include the use of the more potent blood thinner ticagrelor also in patients with stable coronary artery disease.
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Median Giving
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The most recent tax form filed for 2024 lists the following key individuals.

Name Title City State / Province Country
CAROLYN K TUCKER Manager Jacksonville FL US
CAROLYN TUCKER Exec. Director Jacksonville FL US
JULIAN FANT Director Jacksonville FL US
LAWRENCE B MACKENZIE Director Jacksonville FL US
MELINDA A MACKENZIE Director Jacksonville FL US
The full list of key leaders is available to members. Join today!